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Kate Cwynarski Selected Research

PF 956980

11/2010The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment.

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Kate Cwynarski Research Topics

Disease

15Lymphoma (Lymphomas)
01/2022 - 06/2009
9Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2022 - 09/2014
5Neoplasms (Cancer)
01/2022 - 05/2011
5Hodgkin Disease (Hodgkin's Disease)
08/2021 - 06/2009
5B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2018 - 11/2008
3B-Cell Lymphoma (Lymphoma, B Cell)
11/2022 - 12/2019
2Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
01/2021 - 05/2011
2Mucositis
10/2019 - 05/2015
2Burkitt Lymphoma (Burkitt's Lymphoma)
05/2015 - 03/2010
2Multi-centric Castleman's Disease
07/2014 - 01/2010
2AIDS-Related Lymphoma (Lymphoma, AIDS Related)
06/2009 - 05/2009
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
08/2003 - 05/2003
1Cognitive Dysfunction
01/2022
1Neurolymphomatosis
12/2019
1Dyspepsia (Indigestion)
10/2019
1Fatigue
10/2019
1Nausea
10/2019
1Vomiting
10/2019
1Plasmablastic Lymphoma
01/2019
1Infections
05/2015
1Diarrhea
05/2015
1Tumor Lysis Syndrome
05/2015
1Viremia
07/2014
1Non-Hodgkin Lymphoma (Lymphosarcoma)
11/2012
1HIV Infections (HIV Infection)
09/2012
1Leukemia
06/2012
1Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
12/2011
1T-Cell Lymphoma (Lymphoma, T Cell)
05/2011
1Brain Diseases (Brain Disorder)
06/2010
1Multiple Organ Failure (MODS)
01/2010
1Rare Diseases (Rare Disease)
08/2003

Drug/Important Bio-Agent (IBA)

8Rituximab (Mabthera)FDA Link
02/2021 - 01/2010
7Methotrexate (Mexate)FDA LinkGeneric
01/2022 - 05/2016
4Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric
10/2021 - 05/2016
4Cytarabine (Cytosar-U)FDA LinkGeneric
02/2021 - 05/2015
4Doxorubicin (Adriamycin)FDA LinkGeneric
05/2015 - 04/2012
3Bleomycin (Blenoxane)FDA LinkGeneric
02/2015 - 04/2012
3Vinblastine (Vinblastine Sulfate)FDA Link
02/2015 - 04/2012
3Dacarbazine (DIC)FDA LinkGeneric
02/2015 - 04/2012
2Etoposide (VP 16)FDA LinkGeneric
02/2021 - 05/2015
2Proteins (Proteins, Gene)FDA Link
11/2008 - 05/2003
1Chimeric Antigen ReceptorsIBA
11/2022
1axicabtagene ciloleucelIBA
11/2022
1TinIBA
01/2022
1Glucose (Dextrose)FDA LinkGeneric
02/2021
1Saline SolutionIBA
02/2021
1Carmustine (FIVB)FDA Link
02/2021
1Mesna (Coenzyme M)FDA LinkGeneric
02/2021
1SolutionsIBA
02/2021
1Carboplatin (JM8)FDA LinkGeneric
02/2021
1IfosfamideFDA LinkGeneric
02/2021
1Brentuximab VedotinIBA
01/2021
1Mechanistic Target of Rapamycin Complex 1IBA
10/2019
1vistusertibIBA
10/2019
1Bortezomib (Velcade)FDA Link
01/2019
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2018
1Lenalidomide (CC 5013)FDA Link
01/2018
1pixantrone (BBR 2778)IBA
01/2016
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
05/2015
1Vincristine (Oncovin)FDA LinkGeneric
05/2015
1Biological ProductsIBA
09/2014
1EverolimusFDA Link
08/2014
1temsirolimusFDA Link
08/2014
1MTOR InhibitorsIBA
08/2014
1Sirolimus (Rapamycin)FDA Link
08/2014
1Deoxyglucose (2 Deoxy D glucose)IBA
04/2012
1Interferon-alpha (Interferon Alfa)IBA
12/2011
1Zidovudine (Retrovir)FDA LinkGeneric
12/2011
1Anaplastic Lymphoma KinaseIBA
05/2011
1Interleukin-4 (Interleukin 4)IBA
11/2010
1Cytotoxins (Cytolysins)IBA
11/2010
1CytokinesIBA
11/2010
1PF 956980IBA
11/2010
1Thiamine (Aneurin)FDA Link
06/2010
12-phenylacetylenesulfonamideIBA
08/2009
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
06/2009
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
05/2003

Therapy/Procedure

11Therapeutics
11/2022 - 05/2011
10Stem Cell Transplantation
02/2021 - 08/2003
8Drug Therapy (Chemotherapy)
01/2022 - 03/2010
7Highly Active Antiretroviral Therapy (HAART)
05/2015 - 06/2009
2Hematopoietic Stem Cell Transplantation
10/2019 - 08/2003
2Radiotherapy
11/2017 - 05/2016
2Transplantation
06/2012 - 06/2009
1Salvage Therapy
01/2022
1Intravenous Infusions
02/2021
1Art Therapy
09/2012
1Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
06/2009